This article has been prepared with the title "Investigating the reason and quality of sanctity of wine and alcoholic beverages in response to the Book of Qur'an criticism". The author of the book wants to challenge the law of sanctity of wine in Islam with five doubts. The results of the research show that, firstly, wine is forbidden in the divine religions of Judaism and Christianity, and this can be seen in various verses of the Bible. Digestion leaves irreparable damage and fetal alcohol syndrome, which is a wide range of physical disorders and mental and skeletal abnormalities, is created for the fetus. Thirdly, in order to prevent various harms to the human society and his generation, severe punishment has been considered for drunkenness in the Ahadin and Islam, which is ordered in the Torah of stoning and in Islam, the first two times eighty lashes and the third time the death of the drunkard. . Fourthly, not only wine, but any substance that covers the human mind is forbidden in Islam, and fifthly, the leader of the Taliban in Afghanistan, whether at the beginning of the emergence of this group or now that they are the rulers of this country, the use and trade of any drugs and alcohol is prohibited. Said. The type of article is from the series of fundamental articles, the result of which is the improvement of human society planning, and its approach is descriptive-analytical and its method is library.